TTYH2

Across TCGA cell cohorts, TTYH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,877 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TTYH2-associated GO terms across cancer lineages are Nucleotide biosynthetic process, Ribonucleoside triphosphate biosynthetic process, and Oxidative phosphorylation. Each is linked with TTYH2 in more than 13 cancer types. Because this analysis shows association rather than direction, both TTYH2-to-partner and partner-to-TTYH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide biosynthetic process grouped by TTYH2-low versus TTYH2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTYH2→partner) and Y-score (partner→TTYH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleotide biosynthetic process →	+0.068	+1.435	.003	.002	3	14
BONE	Ribonucleoside triphosphate biosynthetic process →	+0.087	+1.571	.002	.002	3	13
URINARY_TRACT	Oxidative phosphorylation →	+0.076	+1.334	.002	.005	3	12
LUNG_SCLC	ATP biosynthetic process →	+0.093	+1.468	.004	.006	3	12
LARGE_INTESTINE	Cytoplasmic translation →	+0.064	+1.232	.002	.004	3	12
LUNG_NSCLC_LUSC	Purine ribonucleoside triphosphate metabolic process →	+0.087	+1.832	.003	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,877 associations by consensus.

Nucleotide biosynthetic process by TTYH2 expression — BONE

Explore this box plot interactively →