TTYH1

Across TCGA cell cohorts, TTYH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,712 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TTYH1-associated GO terms across cancer lineages are Regulation of muscle filament sliding, Maintenance of unfolded protein, and Establishment of epithelial cell apical/basal polarity. Each is linked with TTYH1 in more than 8 cancer types. Because this analysis shows association rather than direction, both TTYH1-to-partner and partner-to-TTYH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of muscle filament sliding grouped by TTYH1-low versus TTYH1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTYH1→partner) and Y-score (partner→TTYH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of muscle filament sliding →	+1.374	+1.140	.003	.009	3	8
URINARY_TRACT	Maintenance of unfolded protein →	+0.121	+1.385	<.001	.002	3	8
BREAST	Establishment of epithelial cell apical/basal polarity →	-0.190	-1.357	<.001	<.001	3	8
URINARY_TRACT	Positive regulation of striated muscle contraction →	-0.278	-1.162	<.001	.004	2	9
URINARY_TRACT	Regulation of myoblast fusion →	+0.097	+1.385	<.001	.003	3	8
URINARY_TRACT	Phospholipid biosynthetic process →	+0.043	+1.266	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,712 associations by consensus.

Regulation of muscle filament sliding by TTYH1 expression — OESOPHAGUS

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