TTYH1

Across TCGA cell cohorts, TTYH1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTYH1-associated genes across cancer lineages are CGB2, TACR3, and PRND. Each is linked with TTYH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTYH1-to-partner and partner-to-TTYH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CGB2 grouped by TTYH1-low versus TTYH1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTYH1→partner) and Y-score (partner→TTYH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CGB2 →	+1.003	+4.234	<.001	.003	3	1
BLOOD_Leukemia	TACR3 →	+0.034	+4.060	<.001	.003	3	1
BLOOD_Leukemia	PRND →	+0.009	+3.874	<.001	.005	3	1
BLOOD_Leukemia	TEX43 →	+0.084	+4.384	<.001	.006	3	1
BLOOD_Leukemia	CCT8L2 →	+0.015	+3.874	<.001	.005	3	1
BLOOD_Leukemia	IQCF6 →	+0.318	+3.769	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

CGB2 by TTYH1 expression — BLOOD_Leukemia

Explore this box plot interactively →