TTTY5

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TTTY5 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated TTTY5 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TTTY5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TTTY5 expression acts as an unfavorable survival marker.

UCEC, ACC, and LIHC are the cancer types where TTTY5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSTertileII,III,IV0.4680.830<.001114view →
ACCDFSTertileAll0.0460.753<.001108view →
LIHCOSTertileII,III,IV0.3200.726<.00190view →
HNSCDFSTertileII,III,IV0.3880.694<.00166view →
STADOSTertileAll0.1420.730<.00118view →
SKCMOSTertileIV0.2260.613.0349view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration