Q-omics provides the consensus-scored TTTY4C profile across patient tissues and cancer cell-line models. TTTY4C expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in CHOL. Additionally, TTTY4C RNA expression shows 130 significant protein co-abundance associations, with the highest sampling consensus in CCRCC. Together, these results highlight CHOL, and CCRCC as cancer lineages where TTTY4C shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes TTTY4C survival associations across molecular data types. TTTY4C RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TTTY4C data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	CHOL (108)	view →

This table ranks reproducible TTTY4C RNA expression–survival associations across cancer types. High TTTY4C expression shows unfavorable associations in CHOL, STAD, BLCA and LUAD, but favorable associations in KIRC. The CHOL Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CHOL as the clearest survival context for TTTY4C RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.024	0.728	<.001	108	view →
STAD	OS	Tertile	All	0.096	0.688	<.001	72	view →
BLCA	DFS	Tertile	All	0.025	0.626	<.001	72	view →
KIRC	DFS	Tertile	III,IV	0.937	0.617	.011	51	view →
LUAD	OS	Tertile	All	0.290	0.686	.002	36	view →

Pink = unfavorable, green = favorable. all 5 lineages →

TTTY4C-CHOL (OS)

Kaplan–Meier survival curve for TTTY4C RNA expression in CHOL: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with TTTY4C in patient tissues and cancer cell lines. In patient samples, TTTY4C shows the broadest associations at the RNA and protein expression levels, with CCRCC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	130	CCRCC (130)	view →
Function (RNA)	127	KIRC (127)	view →