TTTY4B

Across TCGA pan-cancer cohorts, TTTY4B RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated TTTY4B data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TTTY4B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TTTY4B expression acts as an unfavorable survival marker, although some lineages such as KIRC show a favorable association.

SKCM, PAAD, and KIRP are the cancer types where TTTY4B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.179	0.877	<.001	126	view →
PAAD	OS	Tertile	All	0.094	0.640	<.001	72	view →
KIRP	DFS	Tertile	All	0.556	0.883	<.001	30	view →
PRAD	OS	Tertile	All	0.950	0.995	<.001	18	view →
KIRC	DFS	Tertile	IV	0.757	0.307	.049	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TTTY4B–SKCM (OS)

Open the SKCM breakdown →