TTTY25P

Across TCGA pan-cancer cohorts, TTTY25P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated TTTY25P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TTTY25P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TTTY25P expression acts as an unfavorable survival marker, although some lineages such as ESCA and TGCT show a favorable association.

UCEC, KICH, and LUAD are the cancer types where TTTY25P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.169	0.828	<.001	108	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LUAD	OS	Tertile	III,IV	0.305	0.666	.037	54	view →
SKCM	OS	Tertile	III,IV	0.179	0.801	<.001	51	view →
HNSC	DFS	Tertile	II,III,IV	0.178	0.671	<.001	36	view →
LUSC	DFS	Tertile	All	0.588	0.764	.004	24	view →
GBM	OS	Tertile	All	0.132	0.415	.007	18	view →
ESCA	OS	Tertile	III,IV	1.000	0.372	.033	12	view →
LIHC	DFS	Tertile	All	0.342	0.457	.045	9	view →
TGCT	DFS	Tertile	All	1.000	0.636	.049	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

TTTY25P–UCEC (DFS)

Open the UCEC breakdown →