TTTY23B

Across TCGA patient cohorts, TTTY23B RNA expression is significantly associated with the go_rna of many other GO terms, with 292 significant associations in total. LGG shows the largest number of these associations.

The most reproducible TTTY23B-associated GO terms across cancer lineages are Negative regulation of motor neuron apoptotic process, Cellular response to aldehyde, and Regulation of Golgi organization. Each is linked with TTTY23B in more than 1 cancer types. Because this analysis shows association rather than direction, both TTTY23B-to-partner and partner-to-TTTY23B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of motor neuron apoptotic process grouped by TTTY23B-low versus TTTY23B-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY23B→partner) and Y-score (partner→TTTY23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Negative regulation of motor neuron apoptotic process →	+0.085	+0.034	<.001	.005	3	2
LGG	Cellular response to aldehyde →	+0.034	+0.016	.001	.002	3	1
LGG	Regulation of Golgi organization →	+0.019	+0.017	.001	<.001	3	1
LGG	Cellular response to aldosterone →	+0.043	+0.015	.002	.002	3	1
LGG	Regulation of telomere maintenance in response to DNA damage →	+0.016	+0.023	<.001	<.001	3	1
LGG	Regulation of mesodermal cell differentiation →	+0.028	+0.028	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 292 associations by consensus.

Negative regulation of motor neuron apoptotic process by TTTY23B expression — GBM

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