TTTY23

Across TCGA patient cohorts, TTTY23 RNA expression is significantly associated with the mutation status of many other genes, with 78 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TTTY23-associated genes across cancer lineages are NSUN2, ZNF99, and ARHGAP12. Each is linked with TTTY23 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTTY23-to-partner and partner-to-TTTY23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NSUN2 grouped by TTTY23-low versus TTTY23-high in STAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY23→partner) and Y-score (partner→TTTY23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NSUN2 →	+4.610	+0.071	.003	<.001	3	2
LUAD	ZNF99 →	+4.123	+0.022	.003	<.001	3	2
STAD	ARHGAP12 →	+5.095	+0.092	.002	<.001	3	1
STAD	PRAMEF15 →	+5.417	+0.104	.001	<.001	3	1
STAD	TNIP3 →	+5.095	+0.092	.002	<.001	3	1
HNSC	TTLL1 →	+7.954	+0.089	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

NSUN2 by TTTY23 expression — STAD

Explore this box plot interactively →