TTTY20

Across TCGA patient cohorts, TTTY20 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,737 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible TTTY20-associated GO terms across cancer lineages are Protein localization to condensed chromosome, Positive regulation of ubiquitin-protein transferase activity, and Regulation of tumor necrosis factor-mediated signaling pathway. Each is linked with TTTY20 in more than 3 cancer types. Because this analysis shows association rather than direction, both TTTY20-to-partner and partner-to-TTTY20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by TTTY20-low versus TTTY20-high in LIHC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY20→partner) and Y-score (partner→TTTY20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Protein localization to condensed chromosome →	+0.059	+0.055	<.001	.007	2	4
TGCT	Positive regulation of ubiquitin-protein transferase activity →	+0.033	+0.239	.002	.001	3	3
STAD	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.149	+0.059	<.001	.004	3	3
LIHC	DNA integrity checkpoint signaling →	+0.045	+0.063	<.001	.002	3	2
MESO	RNA splicing, via endonucleolytic cleavage and ligation →	+0.028	+0.651	.005	.006	2	3
MESO	Regulation of transcription by RNA polymerase III →	+0.026	+0.369	<.001	.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,737 associations by consensus.

Protein localization to condensed chromosome by TTTY20 expression — LIHC

Explore this box plot interactively →