TTTY1B

Across TCGA pan-cancer cohorts, TTTY1B RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated TTTY1B data layer compared with 1 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TTTY1B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TTTY1B expression acts as an unfavorable survival marker.

SKCM, OV, and LAML are the cancer types where TTTY1B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.043	0.738	<.001	108	view →
OV	OS	Tertile	II,III,IV	0.300	0.691	.027	54	view →
LAML	DFS	Tertile	All	0.140	0.582	.020	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TTTY1B–SKCM (DFS)

Open the SKCM breakdown →