TTTY19

Across TCGA patient cohorts, TTTY19 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,418 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TTTY19-associated GO terms across cancer lineages are Regulation of tumor necrosis factor-mediated signaling pathway, Phospholipid transport, and Translesion synthesis. Each is linked with TTTY19 in more than 3 cancer types. Because this analysis shows association rather than direction, both TTTY19-to-partner and partner-to-TTTY19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tumor necrosis factor-mediated signaling pathway grouped by TTTY19-low versus TTTY19-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY19→partner) and Y-score (partner→TTTY19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.093	+0.077	<.001	.002	3	3
ESCA	Phospholipid transport →	+0.078	+0.065	<.001	.006	2	4
STAD	Translesion synthesis →	+0.100	+0.084	<.001	.003	3	3
ESCA	Positive regulation of organic acid transport →	+0.092	+0.080	<.001	.001	3	3
ESCA	Regulation of synaptic plasticity →	+0.059	+0.104	<.001	.001	2	4
STAD	Glycosyl compound metabolic process →	+0.091	+0.096	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,418 associations by consensus.

Regulation of tumor necrosis factor-mediated signaling pathway by TTTY19 expression — STAD

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