TTTY14

Across TCGA patient cohorts, TTTY14 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,240 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TTTY14-associated proteins across cancer lineages are DDX3X, DDX3Y, and DDX3Y_S592. Each is linked with TTTY14 in more than 6 cancer types. Because this analysis shows association rather than direction, both TTTY14-to-partner and partner-to-TTTY14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTTY14 versus DDX3X in HNSC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY14→partner) and Y-score (partner→TTTY14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DDX3X →	-0.360	-1.006	<.001	<.001	3	7
PDAC	DDX3Y →	+2.738	+1.741	<.001	<.001	3	7
PDAC	DDX3Y_S592 →	+2.709	+1.739	<.001	<.001	3	7
GBM	EIF1AY →	+2.943	+2.040	<.001	<.001	3	7
COAD	RPS4Y1 →	+2.018	+0.178	<.001	<.001	3	7
GBM	DDX3Y_S63 →	+1.837	+2.144	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,240 associations by consensus.

TTTY14 vs DDX3X — HNSC

Explore this scatter interactively →