TTPAL

Across TCGA patient cohorts, TTPAL protein abundance is significantly associated with the RNA expression of many other genes, with 8,771 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TTPAL-associated genes across cancer lineages are BLCAP, GLCCI1, and EXOC6. Each is linked with TTPAL in more than 3 cancer types. Because this analysis shows association rather than direction, both TTPAL-to-partner and partner-to-TTPAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTPAL versus BLCAP in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTPAL→partner) and Y-score (partner→TTPAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BLCAP →	+0.467	+0.187	<.001	.001	3	4
HNSC	GLCCI1 →	-0.616	-0.279	<.001	<.001	3	3
HNSC	EXOC6 →	-0.692	-0.493	<.001	<.001	3	3
BRCA	ANGPTL4 →	+1.732	+0.295	<.001	<.001	3	3
BRCA	PSMG1 →	+0.565	+0.247	<.001	.001	3	3
HNSC	LINC00539 →	-0.330	-0.255	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,771 associations by consensus.

TTPAL vs BLCAP — LSCC

Explore this scatter interactively →