TTPAL

Across TCGA patient cohorts, TTPAL protein abundance is significantly associated with the protein abundance of many other proteins, with 20,470 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTPAL-associated proteins across cancer lineages are CDKN2AIP, STAG1, and IRF2. Each is linked with TTPAL in more than 5 cancer types. Because this analysis shows association rather than direction, both TTPAL-to-partner and partner-to-TTPAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTPAL versus CDKN2AIP in BRCA, with a Pearson correlation of -0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTPAL→partner) and Y-score (partner→TTPAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDKN2AIP →	-0.343	-0.309	<.001	<.001	3	6
HNSC	STAG1 →	-0.238	-0.300	<.001	.002	3	5
HNSC	IRF2 →	-0.343	-0.453	<.001	<.001	3	5
BRCA	PNISR →	-0.271	-0.234	<.001	<.001	3	5
BRCA	HMGA1_S8 →	-1.400	-0.240	<.001	<.001	3	4
OV	RPL10 →	+0.286	+0.257	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,470 associations by consensus.

TTPAL vs CDKN2AIP — BRCA

Explore this scatter interactively →