TTPAL

Across TCGA cell cohorts, TTPAL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,372 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTPAL-associated GO terms across cancer lineages are Negative regulation of cilium assembly, Microtubule polymerization, and Nuclear transport. Each is linked with TTPAL in more than 14 cancer types. Because this analysis shows association rather than direction, both TTPAL-to-partner and partner-to-TTPAL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cilium assembly grouped by TTPAL-low versus TTPAL-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTPAL→partner) and Y-score (partner→TTPAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of cilium assembly →	+0.088	+1.474	<.001	<.001	3	14
PANCREAS	Microtubule polymerization →	+0.101	+0.772	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.084	+0.952	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitotic centrosome separation →	+0.130	+0.776	.002	.002	2	15
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.084	+1.000	<.001	<.001	3	14
STOMACH	Nuclear export →	+0.078	+1.149	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

Negative regulation of cilium assembly by TTPAL expression — STOMACH

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