TTLL6

Across TCGA cell cohorts, TTLL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,765 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TTLL6-associated GO terms across cancer lineages are Cytoskeleton-dependent intracellular transport, Transport along microtubule, and Regulation of transcription initiation by RNA polymerase II. Each is linked with TTLL6 in more than 7 cancer types. Because this analysis shows association rather than direction, both TTLL6-to-partner and partner-to-TTLL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent intracellular transport grouped by TTLL6-low versus TTLL6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTLL6→partner) and Y-score (partner→TTLL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.089	+1.262	<.001	<.001	3	7
LUNG_SCLC	Transport along microtubule →	+0.082	+1.254	<.001	<.001	2	8
BONE	Regulation of transcription initiation by RNA polymerase II →	+0.054	+2.289	.003	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Purine nucleoside triphosphate metabolic process →	+0.054	+0.062	.004	.004	3	7
LIVER	Organelle fusion →	+0.055	+1.395	.004	.004	2	7
BONE	Regulation of DNA-templated transcription initiation →	+0.057	+2.105	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,765 associations by consensus.

Cytoskeleton-dependent intracellular transport by TTLL6 expression — LUNG_SCLC

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