TTLL2

Across TCGA patient cohorts, TTLL2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,749 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTLL2-associated genes across cancer lineages are PRODH, SEZ6L, and SEPTIN3. Each is linked with TTLL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTLL2-to-partner and partner-to-TTLL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTLL2 versus PRODH in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTLL2→partner) and Y-score (partner→TTLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.835	+0.952	.001	<.001	3	1
GBM	SEZ6L →	+1.995	+1.127	.002	.001	3	1
GBM	SEPTIN3 →	+1.053	+1.026	.003	<.001	3	1
GBM	RASL10A →	+0.695	+0.887	.007	.001	3	1
GBM	NEFH →	+1.338	+1.473	.004	<.001	3	1
GBM	ARSA →	-0.390	-0.964	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,749 associations by consensus.

TTLL2 vs PRODH — GBM

Explore this scatter interactively →