TTLL10

Across TCGA pan-cancer cohorts, TTLL10 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TTLL10 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TTLL10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TTLL10 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD, THYM, and LIHC are the cancer types where TTLL10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.053	0.835	<.001	48	view →
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
LIHC	DFS	Median	II,III,IV	0.020	0.427	<.001	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	DFS	Median	All	0.422	0.198	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TTLL10–LUAD (OS)

Open the LUAD breakdown →