TTLL1

Across TCGA patient cohorts, TTLL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,884 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTLL1-associated proteins across cancer lineages are TRIM2, IFT27, and UNC13D. Each is linked with TTLL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TTLL1-to-partner and partner-to-TTLL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTLL1 versus TRIM2 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTLL1→partner) and Y-score (partner→TTLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRIM2 →	+0.576	+0.589	<.001	<.001	3	5
BRCA	IFT27 →	+0.530	+0.553	<.001	<.001	3	5
LSCC	UNC13D →	-0.471	-0.641	<.001	<.001	3	4
HNSC	XAF1_S268 →	-0.661	-0.597	<.001	<.001	3	4
LSCC	XRCC5 →	+0.194	+0.514	.001	<.001	3	4
BRCA	COMT →	+0.416	+0.426	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,884 associations by consensus.

TTLL1 vs TRIM2 — HNSC

Explore this scatter interactively →