TTLL1

Across TCGA cell cohorts, TTLL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,435 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTLL1-associated GO terms across cancer lineages are Autophagy, Process utilizing autophagic mechanism, and Flagellated sperm motility. Each is linked with TTLL1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TTLL1-to-partner and partner-to-TTLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagy grouped by TTLL1-low versus TTLL1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTLL1→partner) and Y-score (partner→TTLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Autophagy →	+0.064	+1.182	.002	<.001	3	13
KIDNEY	Process utilizing autophagic mechanism →	+0.064	+1.182	.002	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.108	-1.128	.003	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	COPII-coated vesicle budding →	+0.076	+1.138	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.108	-1.128	.003	<.001	3	12
LARGE_INTESTINE	Vesicle targeting, to, from or within Golgi →	+0.099	+0.797	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,435 associations by consensus.

Autophagy by TTLL1 expression — KIDNEY

Explore this box plot interactively →