TTF1

Across TCGA cell cohorts, TTF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,232 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTF1-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Nucleic acid transport, and RNA transport. Each is linked with TTF1 in more than 18 cancer types. Because this analysis shows association rather than direction, both TTF1-to-partner and partner-to-TTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by TTF1-low versus TTF1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTF1→partner) and Y-score (partner→TTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Immunoglobulin heavy chain V-D-J recombination →	+0.203	+0.688	<.001	<.001	3	19
SOFT_TISSUE	Nucleic acid transport →	+0.103	+0.728	<.001	.001	3	18
SOFT_TISSUE	RNA transport →	+0.103	+0.728	<.001	.001	3	18
SOFT_TISSUE	Establishment of RNA localization →	+0.101	+0.820	<.001	<.001	3	18
SOFT_TISSUE	RNA export from nucleus →	+0.130	+0.792	<.001	<.001	3	18
BONE	Regulation of hematopoietic stem cell differentiation →	+0.119	+0.623	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,232 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by TTF1 expression — URINARY_TRACT

Explore this box plot interactively →