TTC9

Across TCGA patient cohorts, TTC9 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,616 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TTC9-associated proteins across cancer lineages are TTC9_S15, CDC42BPB, and IKZF2_S433. Each is linked with TTC9 in more than 8 cancer types. Because this analysis shows association rather than direction, both TTC9-to-partner and partner-to-TTC9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC9 versus TTC9_S15 in OV, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC9→partner) and Y-score (partner→TTC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TTC9_S15 →	+1.487	+1.648	<.001	<.001	3	9
BRCA	CDC42BPB →	+0.188	+0.730	.008	.001	3	5
OV	IKZF2_S433 →	+0.722	+1.042	.001	.004	3	5
HNSC	EPS8L1 →	+0.805	+1.018	<.001	<.001	3	5
LSCC	TACSTD2 →	+0.604	+0.828	<.001	<.001	3	5
UCEC	SFN →	+1.100	+1.184	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,616 associations by consensus.

TTC9 vs TTC9_S15 — OV

Explore this scatter interactively →