TTC7A

Across TCGA pan-cancer cohorts, TTC7A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TTC7A data layer compared with 26 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TTC7A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TTC7A expression acts as an unfavorable survival marker.

LUAD and HNSC are the cancer types where TTC7A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.170	0.659	<.001	17	view →
HNSC	OS	Median	All	0.167	0.710	.005	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TTC7A–LUAD (DFS)

Open the LUAD breakdown →