TTC4

Across TCGA patient cohorts, TTC4 protein abundance is significantly associated with the RNA expression of many other genes, with 14,429 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TTC4-associated genes across cancer lineages are MRPL37, EBNA1BP2, and NRDC. Each is linked with TTC4 in more than 7 cancer types. Because this analysis shows association rather than direction, both TTC4-to-partner and partner-to-TTC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC4 versus MRPL37 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC4→partner) and Y-score (partner→TTC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL37 →	+0.597	+0.291	<.001	<.001	3	8
UCEC	EBNA1BP2 →	+0.835	+0.240	<.001	.003	3	7
LUAD	NRDC →	+0.533	+0.283	<.001	<.001	3	7
UCEC	CDCA8 →	+1.175	+0.277	<.001	<.001	3	7
UCEC	SF3A3 →	+0.590	+0.250	<.001	.002	3	7
BRCA	DEPDC1 →	+0.934	+0.287	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,429 associations by consensus.

TTC4 vs MRPL37 — UCEC

Explore this scatter interactively →