TTC39C-AS1

Across TCGA pan-cancer cohorts, TTC39C-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TTC39C-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TTC39C-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TTC39C-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, KIRC, and BRCA are the cancer types where TTC39C-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.730	0.592	<.001	115	view →
KIRC	OS	Tertile	All	0.545	0.729	<.001	64	view →
BRCA	OS	Median	All	0.660	0.499	<.001	53	view →
SKCM	OS	Quartile	All	0.479	0.282	.002	52	view →
PAAD	DFS	Median	II,III,IV	0.542	0.352	<.001	51	view →
LGG	OS	Median	All	0.724	0.891	<.001	51	view →
ACC	OS	Median	III,IV	0.569	0.862	.006	24	view →
LUAD	DFS	Tertile	All	0.843	0.742	.005	22	view →
LIHC	OS	Median	III,IV	0.639	0.396	.004	21	view →
MESO	DFS	Median	IV	0.558	0.212	.004	15	view →
UVM	DFS	Median	II,III,IV	0.422	0.788	.020	10	view →
COAD	OS	Quartile	All	0.464	0.683	.024	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TTC39C-AS1–HNSC (DFS)

Open the HNSC breakdown →