TTC39B

Across TCGA patient cohorts, TTC39B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,200 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TTC39B-associated proteins across cancer lineages are TTC39B_S524, NUP35_T265, and TTC39B_S120. Each is linked with TTC39B in more than 4 cancer types. Because this analysis shows association rather than direction, both TTC39B-to-partner and partner-to-TTC39B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC39B versus TTC39B_S524 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC39B→partner) and Y-score (partner→TTC39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TTC39B_S524 →	+1.053	+0.732	<.001	<.001	3	5
BRCA	NUP35_T265 →	-0.496	-0.510	<.001	.002	3	5
GBM	TTC39B_S120 →	+1.203	+0.755	<.001	.001	3	4
GBM	MTAP →	+0.610	+0.538	.003	<.001	2	5
OV	WDR43 →	-0.291	-0.645	.001	.004	3	4
OV	WDR43_S77 →	-0.645	-0.644	.007	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,200 associations by consensus.

TTC39B vs TTC39B_S524 — HNSC

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