TTC39B

Across TCGA patient cohorts, TTC39B mutation is significantly associated with the RNA expression of many other genes, with 1,798 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC39B-associated genes across cancer lineages are LINC01216, MIR4743, and DUTP8. Each is linked with TTC39B in more than 2 cancer types. Because this analysis shows association rather than direction, both TTC39B-to-partner and partner-to-TTC39B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01216 grouped by TTC39B-low versus TTC39B-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC39B→partner) and Y-score (partner→TTC39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC01216 →	+0.060	+4.327	.009	.009	3	3
BRCA	MIR4743 →	+0.221	+4.739	<.001	.005	3	2
COAD	DUTP8 →	+0.490	+4.799	<.001	.001	3	2
COAD	SPTLC1P5 →	+0.481	+3.831	<.001	.007	3	2
COAD	RPS8P6 →	+0.267	+3.831	<.001	.007	3	2
COAD	PRPF19P1 →	+0.119	+3.993	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,798 associations by consensus.

LINC01216 by TTC39B expression — HNSC

Explore this box plot interactively →