TTC39B

Across TCGA cell cohorts, TTC39B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,538 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TTC39B-associated GO terms across cancer lineages are Regulation of macroautophagy, Positive regulation of ubiquitin-dependent protein catabolic process, and Response to endoplasmic reticulum stress. Each is linked with TTC39B in more than 7 cancer types. Because this analysis shows association rather than direction, both TTC39B-to-partner and partner-to-TTC39B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by TTC39B-low versus TTC39B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC39B→partner) and Y-score (partner→TTC39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of macroautophagy →	+0.049	+0.730	<.001	.003	3	8
BLOOD_Leukemia	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.044	+0.821	<.001	<.001	3	8
BONE	Response to endoplasmic reticulum stress →	+0.091	+1.495	<.001	<.001	3	8
BONE	Cotranslational protein targeting to membrane →	+0.130	+1.194	<.001	<.001	3	8
BREAST	Protein localization to perinuclear region of cytoplasm →	+0.074	+0.789	.005	.003	3	7
BONE	Regulation of ferroptosis →	+0.140	+1.223	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,538 associations by consensus.

Regulation of macroautophagy by TTC39B expression — SOFT_TISSUE

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