TTC39A

Across TCGA cell cohorts, TTC39A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,780 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TTC39A-associated GO terms across cancer lineages are Establishment of apical/basal cell polarity, Negative regulation of NK T cell activation, and Negative regulation of cell fate commitment. Each is linked with TTC39A in more than 11 cancer types. Because this analysis shows association rather than direction, both TTC39A-to-partner and partner-to-TTC39A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of apical/basal cell polarity grouped by TTC39A-low versus TTC39A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC39A→partner) and Y-score (partner→TTC39A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment of apical/basal cell polarity →	-0.188	-2.574	<.001	<.001	3	12
BLOOD_Lymphoma	Negative regulation of NK T cell activation →	+0.368	+1.252	.003	<.001	3	11
STOMACH	Negative regulation of cell fate commitment →	-0.553	-1.724	.005	<.001	3	10
KIDNEY	Mammary gland development →	+0.162	+3.074	<.001	<.001	3	10
LARGE_INTESTINE	Fatty acid catabolic process →	+0.085	+1.737	<.001	<.001	3	10
OVARY	Endoplasmic reticulum unfolded protein response →	+0.095	+1.447	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,780 associations by consensus.

Establishment of apical/basal cell polarity by TTC39A expression — LUNG_SCLC

Explore this box plot interactively →