TTC38

Across TCGA pan-cancer cohorts, TTC38 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TTC38 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TTC38 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TTC38 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where TTC38 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.912	.014	72	view →
PDAC	DFS	Median	All	0.510	0.312	<.001	69	view →
CCRCC	OS	Quartile	II,III,IV	1.000	0.559	.002	36	view →
HNSC	DFS	Median	III,IV	0.935	1.000	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TTC38–COAD (DFS)

Open the COAD breakdown →