Across TCGA patient cohorts, TTC37 mutation is significantly associated with the total protein of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC37-associated genes across cancer lineages are STAT3_pY705, MYH11, and Cyclin-E2. Each is linked with TTC37 in more than 2 cancer types. Because this analysis shows association rather than direction, both TTC37-to-partner and partner-to-TTC37 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC37→partner) and Y-score (partner→TTC37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.300	-1.584	<.001	.007	3	3
COAD	MYH11 →	-1.618	-3.450	.005	.005	3	3
COAD	Cyclin-E2 →	+0.207	+2.330	.048	.020	3	3
LUSC	Notch1 →	+0.286	+2.834	<.001	.035	2	3
UCEC	A-Raf_pS299 →	-0.110	-1.925	.001	.004	3	2
UCEC	FoxM1 →	+0.175	+1.347	.018	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Exploration

TTC37 survival (RNA) · tumor vs normal (RNA) · all TTC37 data types