TTC33

Across TCGA pan-cancer cohorts, TTC33 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TTC33 data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher TTC33 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TTC33 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CESC and UCEC are the cancer types where TTC33 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.616	0.874	.021	12	view →
UCEC	DFS	Median	All	1.000	0.631	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TTC33–CESC (OS)

Open the CESC breakdown →