Across TCGA pan-cancer cohorts, TTC30A mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TTC30A data layer compared with 29 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TTC30A mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TTC30A expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

UCEC, GBM, and LUAD are the cancer types where TTC30A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.354	1.000	.036	8	view →
GBM	OS	Median	All	0.263	0.469	.007	7	view →
LUAD	OS	Median	All	1.000	0.936	.005	5	view →
CCRCC	OS	Tertile	All	0.774	1.000	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: TTC30A tumor-vs-normal RNA expression · all TTC30A data types