TTC30A

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TTC30A mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTC30A-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and GAPDH. Each is linked with TTC30A in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC30A-to-partner and partner-to-TTC30A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC30A→partner) and Y-score (partner→TTC30A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.076-1.673.021.04032
UCECEGFR_pY1068 →-0.289-3.169<.001<.00132
UCECGAPDH →+0.361+1.700.041.04032
UCECMEK1 →+0.478+2.263<.001<.00132
UCECp27_pT198 →+0.095+1.652.006.00632
UCECAkt_pT308 →+0.444+2.459.032.01832
Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration