Across TCGA cell cohorts, TTC30A mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TTC30A-associated genes across cancer lineages are UBQLN3, OR2V2, and OR4N5. Each is linked with TTC30A in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC30A-to-partner and partner-to-TTC30A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC30A→partner) and Y-score (partner→TTC30A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	UBQLN3 →	+0.011	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR2V2 →	+0.038	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR4N5 →	+0.022	+4.662	<.001	.005	3	1
SKIN	LAIR2 →	+0.105	+3.510	<.001	.003	3	1
SKIN	DMRTC1B →	+0.049	+3.345	.003	.007	3	1
LARGE_INTESTINE	LILRB1 →	+0.042	+3.700	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

TTC30A survival (RNA) · tumor vs normal (RNA) · all TTC30A data types