TTC3

Across TCGA patient cohorts, TTC3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,032 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TTC3-associated genes across cancer lineages are IFT27, OGN, and INO80B. Each is linked with TTC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TTC3-to-partner and partner-to-TTC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC3 versus IFT27 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC3→partner) and Y-score (partner→TTC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IFT27 →	+0.646	+0.412	.001	.002	3	3
COAD	OGN →	+2.784	+1.265	<.001	.001	3	3
HNSC	INO80B →	+0.539	+0.445	.001	.001	3	3
BRCA	ZNF835 →	+0.389	+0.343	.002	.001	3	3
BRCA	SPATA6 →	+0.858	+0.431	<.001	<.001	3	3
HNSC	CTSL →	-1.419	-0.532	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,032 associations by consensus.

TTC3 vs IFT27 — HNSC

Explore this scatter interactively →