TTC3

Across TCGA cell cohorts, TTC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,504 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TTC3-associated GO terms across cancer lineages are Cytosolic transport, Endosomal transport, and Retrograde transport, endosome to Golgi. Each is linked with TTC3 in more than 14 cancer types. Because this analysis shows association rather than direction, both TTC3-to-partner and partner-to-TTC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by TTC3-low versus TTC3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC3→partner) and Y-score (partner→TTC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.073	+0.923	<.001	<.001	3	15
BREAST	Endosomal transport →	+0.058	+0.963	.001	.002	2	15
OVARY	Retrograde transport, endosome to Golgi →	+0.071	+1.156	<.001	<.001	3	14
PANCREAS	Vesicle targeting →	+0.067	+0.899	<.001	.002	3	14
URINARY_TRACT	Transport along microtubule →	+0.054	+1.022	.001	.002	3	13
STOMACH	Peptidyl-serine modification →	+0.080	+1.038	.005	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,504 associations by consensus.

Cytosolic transport by TTC3 expression — UPPER_AERODIGESTIVE_TRACT

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