TTC28

Across TCGA cell cohorts, TTC28 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,487 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TTC28-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and tRNA transcription. Each is linked with TTC28 in more than 12 cancer types. Because this analysis shows association rather than direction, both TTC28-to-partner and partner-to-TTC28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TTC28-low versus TTC28-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC28→partner) and Y-score (partner→TTC28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.170	+1.144	<.001	.003	3	13
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.172	+1.273	<.001	.001	3	13
STOMACH	tRNA transcription →	+0.108	+2.079	<.001	<.001	3	13
SKIN	Positive regulation of sterol biosynthetic process →	+0.118	+1.022	<.001	<.001	3	13
SKIN	Positive regulation of cholesterol biosynthetic process →	+0.118	+1.022	<.001	<.001	3	13
SOFT_TISSUE	Regulation of telomerase RNA localization to Cajal body →	+0.077	+1.334	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,487 associations by consensus.

Negative regulation of myoblast fusion by TTC28 expression — OESOPHAGUS

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