TTC27

Across TCGA patient cohorts, TTC27 protein abundance is significantly associated with the RNA expression of many other genes, with 11,141 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTC27-associated genes across cancer lineages are CENPA, NOL10, and PNO1. Each is linked with TTC27 in more than 5 cancer types. Because this analysis shows association rather than direction, both TTC27-to-partner and partner-to-TTC27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC27 versus CENPA in BRCA, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC27→partner) and Y-score (partner→TTC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CENPA →	+1.029	+0.248	<.001	<.001	3	6
HNSC	NOL10 →	+0.585	+0.289	<.001	<.001	3	6
HNSC	PNO1 →	+0.668	+0.269	.002	.001	3	6
BRCA	GFRA1 →	-2.419	-0.253	<.001	<.001	3	6
COAD	LMOD1 →	-0.925	-0.155	<.001	.001	3	6
LUAD	SHE →	-0.702	-0.167	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,141 associations by consensus.

TTC27 vs CENPA — BRCA

Explore this scatter interactively →