Across TCGA patient cohorts, TTC25 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,170 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TTC25-associated proteins across cancer lineages are WDR35, IFT140, and TTC21B. Each is linked with TTC25 in more than 7 cancer types. Because this analysis shows association rather than direction, both TTC25-to-partner and partner-to-TTC25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC25→partner) and Y-score (partner→TTC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR35 →	+0.398	+1.346	<.001	<.001	3	8
BRCA	IFT140 →	+0.475	+0.659	<.001	<.001	3	8
OV	TTC21B →	+0.308	+0.858	<.001	<.001	3	7
BRCA	WDR19 →	+0.442	+0.752	<.001	<.001	3	7
UCEC	NME7 →	+0.320	+1.164	<.001	<.001	3	7
UCEC	DYNC2H1 →	+0.482	+0.979	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,170 associations by consensus.

Exploration

TTC25 survival (RNA) · tumor vs normal (RNA) · all TTC25 data types