Across TCGA cell cohorts, TTC24 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TTC24-associated genes across cancer lineages are SLC6A5, MYL10, and PSG7. Each is linked with TTC24 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC24-to-partner and partner-to-TTC24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC24→partner) and Y-score (partner→TTC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SLC6A5 →	+0.023	+4.906	<.001	.006	3	1
LUNG_SCLC	MYL10 →	+0.093	+3.938	<.001	<.001	3	1
LUNG_SCLC	PSG7 →	+0.076	+3.070	<.001	.009	3	1
CNS	RNASE11 →	+0.062	+5.321	<.001	.005	3	1
CNS	OR11A1 →	+0.016	+5.321	<.001	.005	3	1
LARGE_INTESTINE	COX6A2 →	+0.082	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

TTC24 survival (RNA) · tumor vs normal (RNA) · all TTC24 data types