TTC23

Across TCGA patient cohorts, TTC23 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,050 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TTC23-associated proteins across cancer lineages are ARFGEF2, VSNL1, and PDK1. Each is linked with TTC23 in more than 5 cancer types. Because this analysis shows association rather than direction, both TTC23-to-partner and partner-to-TTC23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC23 versus ARFGEF2 in BRCA, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC23→partner) and Y-score (partner→TTC23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARFGEF2 →	-0.311	-0.548	.002	.001	3	6
BRCA	VSNL1 →	+0.802	+0.759	<.001	<.001	3	4
GBM	PDK1 →	-0.382	-0.296	.006	.004	3	4
BRCA	SEC23B →	-0.357	-0.695	<.001	<.001	3	4
LSCC	SEC24A →	-0.405	-0.475	<.001	<.001	3	4
UCEC	ELOVL1 →	-0.813	-0.751	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,050 associations by consensus.

TTC23 vs ARFGEF2 — BRCA

Explore this scatter interactively →