TTC23

Across TCGA cell cohorts, TTC23 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,789 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TTC23-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with TTC23 in more than 9 cancer types. Because this analysis shows association rather than direction, both TTC23-to-partner and partner-to-TTC23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by TTC23-low versus TTC23-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC23→partner) and Y-score (partner→TTC23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of myoblast fusion →	+0.086	+0.482	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.085	+0.569	<.001	.002	3	10
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.096	+0.531	.002	<.001	3	10
OESOPHAGUS	Endosomal transport →	+0.062	+0.988	<.001	.002	2	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.086	+0.621	<.001	<.001	3	9
PANCREAS	Macroautophagy →	+0.029	+0.448	.009	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,789 associations by consensus.

Regulation of myoblast fusion by TTC23 expression — KIDNEY

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