TTC14

Across TCGA patient cohorts, TTC14 protein abundance is significantly associated with the RNA expression of many other genes, with 10,324 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TTC14-associated genes across cancer lineages are ISOC1, USP6NL, and FBXW11P1. Each is linked with TTC14 in more than 3 cancer types. Because this analysis shows association rather than direction, both TTC14-to-partner and partner-to-TTC14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC14 versus ISOC1 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC14→partner) and Y-score (partner→TTC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ISOC1 →	+0.781	+0.532	.006	.001	3	4
OV	USP6NL →	+1.017	+1.295	<.001	<.001	3	3
GBM	FBXW11P1 →	+0.609	+0.317	<.001	.001	3	3
OV	MCCC1-AS1 →	+0.951	+1.068	.002	.002	3	3
LSCC	CENPF →	+0.742	+0.247	<.001	<.001	3	3
BRCA	C1orf226 →	+0.872	+0.376	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,324 associations by consensus.

TTC14 vs ISOC1 — BRCA

Explore this scatter interactively →