TTC1

Across TCGA cell cohorts, TTC1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,207 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TTC1-associated genes across cancer lineages are DCTN6, RPS16, and POLR2I. Each is linked with TTC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC1-to-partner and partner-to-TTC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC1 versus DCTN6 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC1→partner) and Y-score (partner→TTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DCTN6 →	+0.653	+1.321	<.001	.007	3	1
UPPER_AERODIGESTIVE_TRACT	RPS16 →	+0.753	+1.536	.001	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	POLR2I →	+0.640	+1.754	.001	.008	3	1
UPPER_AERODIGESTIVE_TRACT	PTPRZ1 →	-3.004	-1.438	.002	.002	3	1
UPPER_AERODIGESTIVE_TRACT	RPL28 →	+0.878	+1.975	.002	.002	3	1
UPPER_AERODIGESTIVE_TRACT	PFDN5 →	+0.807	+1.536	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,207 associations by consensus.

TTC1 vs DCTN6 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →