TSTD2

Across TCGA cell cohorts, TSTD2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TSTD2-associated genes across cancer lineages are NXPH1, C4BPA, and CSN1S1. Each is linked with TSTD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSTD2-to-partner and partner-to-TSTD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NXPH1 grouped by TSTD2-low versus TSTD2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSTD2→partner) and Y-score (partner→TSTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	NXPH1 →	+0.262	+3.643	<.001	.006	3	1
BLOOD_Lymphoma	C4BPA →	+0.018	+3.459	<.001	.004	3	1
BLOOD_Lymphoma	CSN1S1 →	+0.069	+3.342	<.001	.008	3	1
BLOOD_Lymphoma	APCS →	+0.062	+3.938	<.001	.001	3	1
BLOOD_Lymphoma	FRMPD4 →	+0.749	+3.836	.001	.006	3	1
BLOOD_Lymphoma	LRRC3B →	+0.031	+3.765	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

NXPH1 by TSTD2 expression — BLOOD_Lymphoma

Explore this box plot interactively →