Q-omics provides the consensus-scored TSSK5P profile across patient tissues and cancer cell-line models. TSSK5P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in CESC. Among the 18 cancer types available for tumor–normal comparison, TSSK5P is differentially expressed in 10, with the highest sampling consensus in THCA. Additionally, TSSK5P RNA expression shows 19,498 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight CESC, THCA, and ACC as cancer lineages where TSSK5P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TSSK5P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TSSK5P survival associations across molecular data types. TSSK5P RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TSSK5P RNA expression–survival associations across cancer types. High TSSK5P expression shows unfavorable associations in CESC, LIHC, MESO, BRCA, ACC and COAD. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CESC as the clearest survival context for TSSK5P RNA expression.
This table summarizes TSSK5P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for TSSK5P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TSSK5P shows lower tumor expression in THCA and higher tumor expression in HNSC, LIHC, KICH, CHOL and LUSC. The THCA box plot shows higher TSSK5P RNA expression in normal versus tumor tissue (log2 FC = −1.499, t-test p < 0.001).
This table shows molecular features associated with TSSK5P in patient tissues and cancer cell lines. In patient samples, TSSK5P shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
