TSSK3

Across TCGA patient cohorts, TSSK3 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSSK3-associated genes across cancer lineages are pDC, MEP, and Mesangial cells. Each is linked with TSSK3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSSK3-to-partner and partner-to-TSSK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by TSSK3-low versus TSSK3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSSK3→partner) and Y-score (partner→TSSK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	pDC →	+0.062	+2.839	.021	.034	3	3
UCEC	MEP →	+0.033	+3.180	.030	.010	3	1
UCEC	Mesangial cells →	-0.056	-3.159	.008	.020	3	1
UCEC	Th2 cells →	+0.275	+2.818	.005	.035	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

pDC by TSSK3 expression — UCEC

Explore this box plot interactively →