Across TCGA patient cohorts, TSSK2 mutation is significantly associated with the RNA expression of many other genes, with 831 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSSK2-associated genes across cancer lineages are RNU1-140P, DHFRP5, and RN7SKP32. Each is linked with TSSK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSSK2-to-partner and partner-to-TSSK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSSK2→partner) and Y-score (partner→TSSK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU1-140P →	+0.224	+5.132	<.001	.002	3	3
UCEC	DHFRP5 →	+0.075	+2.997	<.001	.006	3	3
HNSC	RN7SKP32 →	+0.140	+3.639	<.001	.006	3	2
BLCA	RNU6-755P →	+0.325	+7.640	<.001	.009	3	2
BLCA	RNU6-622P →	+0.328	+7.640	<.001	.009	3	2
HNSC	CCDC137P →	+0.073	+3.321	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 831 associations by consensus.

Exploration

TSSK2 survival (RNA) · tumor vs normal (RNA) · all TSSK2 data types